Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13897596 | 0.89 | SIRT5 (0.48) | SIRT5TBK1 | |
| SCHEMBL13897741 | 0.88 | SIRT5 (0.46) | SIRT5TBK1 | |
| SCHEMBL3865708 | 0.88 | SIRT5 (0.49) | SIRT5TBK1 | |
| SCHEMBL13897635 | 0.86 | SIRT5 (0.48) | SIRT5TBK1 | |
| SCHEMBL13897419 | 0.83 | TBK1 (0.45) | SIRT5TBK1 | |
| SCHEMBL6452492 | 0.79 | TBK1 (0.45) | SIRT5TBK1 | |
| SCHEMBL3880478 | 0.78 | MAPT (0.39) | TBK1 | |
| SCHEMBL3864678 | 0.77 | TBK1 (0.38) | SIRT5TBK1 | |
| SCHEMBL3864671 | 0.77 | TBK1 (0.38) | SIRT5TBK1 | |
| SCHEMBL3865668 | 0.71 | TLR8 (0.49) | SIRT5TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504410-B2 | Chk-, Pdk- and Akt-inhibitory pyrimidines, their production and use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 2009-03-17 | — | — | US | disclosed |