Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120745 | 0.80 | GLO1 (0.64) | GLO1MEN1KMT2AMAPTUSP2 | |
| SCHEMBL5902214 | 0.80 | GLO1 (0.64) | GLO1MEN1KMT2AMAPTUSP2 | |
| SCHEMBL120746 | 0.80 | GLO1 (0.64) | GLO1MEN1KMT2AMAPTUSP2 | |
| SCHEMBL23065899 | 0.76 | GLO1 (0.50) | GLO1MEN1KMT2AMAPTUSP2 | |
| SCHEMBL3512466 | 0.75 | GLO1 (0.62) | GLO1MEN1KMT2AMAPTUSP2 | |
| SCHEMBL11282230 | 0.73 | ALDH1A1 (0.47) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL11282227 | 0.73 | ALDH1A1 (0.47) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL6835330 | 0.73 | CYP1A2 (0.44) | GLO1CA12CA1CA2CA9 | |
| SCHEMBL2825758 | 0.72 | CA12 (0.52) | CA12CA1CA2CA9MAPT | |
| SCHEMBL9278827 | 0.72 | GLO1 (0.75) | GLO1MEN1KMT2AMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504521-B2 | Methods for the preparation of pyrrolotriazine compounds | BRISTOL-MYERS SQUIBB CO. (US) | 2009-03-17 | — | — | US | disclosed |