Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891434 | 0.83 | OPRL1 (0.71) | OPRL1DRD2POLBSMN1; SMN2OPRM1 | |
| SCHEMBL8219466 | 0.81 | GAA (0.47) | DRD2DRD3HTR1ADRD1DRD5 | |
| SCHEMBL6159478 | 0.79 | SLC18A3 (0.47) | DRD2SIGMAR1 | |
| SCHEMBL3902533 | 0.78 | SMN1; SMN2 (0.62) | OPRL1DRD2SMN1; SMN2DRD3HTR1A | |
| SCHEMBL3889338 | 0.78 | DRD2 (0.56) | OPRL1DRD2SMN1; SMN2OPRM1OPRD1 | |
| SCHEMBL3889344 | 0.78 | DRD2 (0.56) | OPRL1DRD2SMN1; SMN2OPRM1OPRD1 | |
| SCHEMBL3888734 | 0.78 | DRD2 (0.60) | DRD2SMN1; SMN2OPRM1OPRK1DRD3 | |
| SCHEMBL13898515 | 0.78 | OPRL1 (0.51) | OPRL1DRD2POLBOPRM1OPRD1 | |
| SCHEMBL6110923 | 0.77 | OPRL1 (0.79) | OPRL1DRD2POLBOPRM1OPRD1 | |
| SCHEMBL8222205 | 0.76 | MAPK1 (0.43) | DRD2DRD3HTR1ADRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |