Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.43 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381873 | 0.81 | OPRL1 (0.75) | OPRL1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL13898516 | 0.78 | OPRL1 (0.51) | OPRL1POLBCCR3SIGMAR1OPRM1 | |
| SCHEMBL3894318 | 0.77 | ALDH1A1 (0.50) | MEN1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL3894096 | 0.76 | DRD2 (0.56) | OPRL1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL3893605 | 0.75 | LMNA (0.49) | OPRL1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL6161715 | 0.75 | SLC6A2 (0.46) | OPRL1ALDH1A1LMNASIGMAR1PARP10 | |
| SCHEMBL7129026 | 0.75 | OPRL1 (0.69) | OPRL1ALDH1A1LMNAPOLBCCR3 | |
| SCHEMBL13898527 | 0.74 | L3MBTL1 (0.63) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL3893161 | 0.74 | OPRL1 (0.68) | OPRL1KMT2APOLBCCR3OPRM1 | |
| SCHEMBL3893429 | 0.74 | DRD2 (0.49) | OPRL1MEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |