Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13233381 | 1.00 | MEN1 (0.42) | MEN1KMT2AGAAALOX5MAPT | |
| SCHEMBL14437205 | 0.93 | EGFR (0.39) | MEN1KMT2AGAAALOX5MAPT | |
| SCHEMBL14437258 | 0.91 | MAPK1 (0.36) | MEN1KMT2AGAAALOX5EGFR | |
| SCHEMBL3025813 | 0.87 | EGFR (0.37) | EGFRMAPK1DYRK1A | |
| SCHEMBL14437218 | 0.87 | HPGD (0.38) | HPGDPIM1CLK2DYRK1APIK3CD | |
| SCHEMBL13956099 | 0.83 | ALOX5 (0.36) | MEN1KMT2AGAAALOX5MAPT | |
| SCHEMBL4871699 | 0.82 | CDK1 (0.49) | MEN1KMT2AGAAALOX5MAPT | |
| SCHEMBL4872298 | 0.82 | CDK1 (0.49) | MEN1KMT2AGAAALOX5MAPT | |
| SCHEMBL4866405 | 0.82 | CDK1 (0.49) | MEN1KMT2AGAAALOX5MAPT | |
| SCHEMBL14452559 | 0.80 | IRAK4 (0.38) | ALOX5MAPTEGFRMAPK1CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2037270-A2 | Tumor models employing green fluorescent protein | F. HOFFMANN-LA ROCHE AG (CH) | 2009-03-18 | — | — | EP | disclosed |
| EP-1840570-A1 | Tumor models employing green fluorescent protein | F. HOFFMANN-LA ROCHE AG (CH) | 2007-10-03 | — | — | EP | disclosed |