Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.41 |
| ▸ | PGK2 | P07205 | 3/20 | 0.41 |
| ▸ | PTPRB | P23467 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045187 | 0.84 | PGK1 (0.50) | PGK1PGK2PTPRBTHRATHRB | |
| SCHEMBL9549401 | 0.84 | PPARD (0.41) | PGK1PGK2PTPRBPTGS1PTGS2 | |
| SCHEMBL9464672 | 0.83 | PGK1 (0.38) | PGK1PGK2PTPRBPTGS1PTGS2 | |
| SCHEMBL15268039 | 0.81 | ESR1 (0.52) | THRATHRBESR1ESR2 | |
| SCHEMBL6313998 | 0.80 | PGK1 (0.63) | PGK1PGK2PTPRBPTGS1PTGS2 | |
| SCHEMBL911758 | 0.77 | MEN1 (0.55) | CA1CA2MEN1KMT2AL3MBTL1 | |
| SCHEMBL10749060 | 0.76 | MEN1 (0.54) | CA1CA2MEN1KMT2AL3MBTL1 | |
| SCHEMBL15101340 | 0.76 | MAPT (0.38) | PGK1PGK2PTGS1PTGS2HMGB1 | |
| SCHEMBL18363067 | 0.76 | ENPP2 (0.41) | PGK1PGK2 | |
| SCHEMBL5663059 | 0.74 | PGK1 (0.50) | PGK1PGK2PTPRBTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7510809-B2 | Electrophotographic photoreceptor with two layer charge transfer layer, and apparatus utilizing the same | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-03-31 | — | — | US | disclosed |