Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252507 | 0.95 | NPSR1 (0.53) | THRBNPSR1GAAEPHX1KDM4E | |
| SCHEMBL13899143 | 0.92 | NPSR1 (0.51) | THRBNPSR1GAAEPHX1KDM4E | |
| SCHEMBL13899369 | 0.90 | NPSR1 (0.52) | THRBNPSR1GAAEPHX1KDM4E | |
| SCHEMBL13899144 | 0.87 | THRB (0.50) | THRBNPSR1GAAEPHX1KDM4E | |
| SCHEMBL13899225 | 0.85 | NPSR1 (0.60) | THRBNPSR1GAAALDH1A1LMNA | |
| SCHEMBL10093589 | 0.84 | CNR1 (0.48) | NPSR1GAAEPHX2ALDH1A1LMNA | |
| SCHEMBL13899382 | 0.83 | NPC1 (0.57) | THRBNPSR1ALDH1A1LMNATSHR | |
| SCHEMBL18364750 | 0.83 | NPSR1 (0.55) | NPSR1GAAEPHX1KDM4EEPHX2 | |
| SCHEMBL13899407 | 0.83 | NPSR1 (0.60) | THRBNPSR1ALDH1A1LMNAHTT | |
| SCHEMBL4340532 | 0.83 | EPHX2 (0.48) | THRBNPSR1GAAEPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498394-B2 | (Meth)acrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498394-B2 | (Meth)acrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-03-03 | — | — | US | disclosed |