SCHEMBL4340532

SCHEMBL4340532

C=CC(=O)OCCNC(=O)Nc1ccc(C(=O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.48
NAMPT P43490 3/20 0.46
MAPK1 P28482 2/20 0.45
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
HPGD P15428 1/20 0.45
RAB9A P51151 1/20 0.45
NPSR1 Q6W5P4 2/20 0.42
GAA P10253 1/20 0.42
CASR P41180 1/20 0.42
THRB P10828 1/20 0.41
NR1H4 Q96RI1 1/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 1/20 0.40
USP2 O75604 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3252507 0.87 NPSR1 (0.53) EPHX2MAPK1NPC1LMNAHPGD
SCHEMBL1735862 0.86 RAB9A (0.47) MAPK1NPC1LMNAHPGDRAB9A
SCHEMBL10093589 0.85 CNR1 (0.48) EPHX2MAPK1NPC1LMNAHPGD
SCHEMBL13899143 0.85 NPSR1 (0.51) LMNANPSR1GAATHRBHDAC1
SCHEMBL3253043 0.85 GAA (0.54) MAPK1NPC1LMNAHPGDRAB9A
SCHEMBL13899369 0.83 NPSR1 (0.52) EPHX2LMNANPSR1GAATHRB
SCHEMBL13899153 0.83 THRB (0.50) EPHX2NPC1LMNARAB9ANPSR1
SCHEMBL3242480 0.82 RAB9A (0.43) NAMPTMAPK1NPC1LMNAHPGD
SCHEMBL3252353 0.82 NPC1 (0.43) MAPK1NPC1LMNAHPGDRAB9A
SCHEMBL21950052 0.81 TGM2 (0.55) NAMPTMAPK1NPC1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 EP disclosed
US-10649337-B2 Positive type lithographic printing plate precursor, method of producing same, and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2020-05-12 US disclosed
EP-3521927-A1 POSITIVE PLANOGRAPHIC PRINTING ORIGINAL PLATE AND METHOD FOR MANUFACTURING SAME, AND METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2019-08-07 EP disclosed
US-20190212652-A1 POSITIVE TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-07-11 US disclosed
US-20090246693-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed