Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.47 |
| ▸ | PPARA | Q07869 | 15/20 | 0.47 |
| ▸ | PPARD | Q03181 | 11/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13899527 | 0.94 | FFAR1 (0.49) | PPARGPPARAPPARDFFAR1SMPD1 | |
| SCHEMBL13899531 | 0.90 | PPARG (0.50) | PPARGPPARAPPARDFFAR1SMPD1 | |
| SCHEMBL13899198 | 0.83 | PPARA (0.54) | PPARGPPARAPPARDFFAR1SMPD1 | |
| SCHEMBL10184595 | 0.82 | PPARA (0.54) | PPARGPPARAPPARDFFAR1SMPD1 | |
| SCHEMBL10184378 | 0.80 | PPARG (0.50) | PPARGPPARAPPARDFFAR1SMPD1 | |
| SCHEMBL13899475 | 0.80 | PPARG (0.50) | PPARGPPARAPPARDFFAR1SMPD1 | |
| SCHEMBL13899289 | 0.80 | PPARG (0.39) | PPARGPPARAFFAR1 | |
| SCHEMBL13899504 | 0.78 | ALDH1A1 (0.37) | PPARG | |
| SCHEMBL13899524 | 0.78 | ALDH1A1 (0.37) | PPARG | |
| SCHEMBL10185914 | 0.76 | FFAR1 (0.56) | PPARGPPARAPPARDFFAR1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507757-B2 | Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-03-24 | — | — | US | disclosed |
| US-7507757-B2 | Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-03-24 | — | — | US | disclosed |