Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078909 | 0.87 | IDO1 (0.54) | IDO1MEN1GAAMAPTKMT2A | |
| SCHEMBL11214170 | 0.84 | GAA (0.51) | IDO1MEN1GAAMAPTKMT2A | |
| SCHEMBL7531116 | 0.82 | ESR1 (0.54) | IDO1MEN1GAAMAPTKMT2A | |
| SCHEMBL10867555 | 0.80 | IDO1 (0.42) | IDO1MEN1ALDH1A1GAAMAPT | |
| SCHEMBL1581774 | 0.79 | IDO1 (0.65) | IDO1MEN1GAAMAPTKMT2A | |
| SCHEMBL10331769 | 0.77 | ESR1 (0.48) | MEN1GAAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4958922 | 0.76 | TTR (0.65) | MEN1KMT2ATTRLTA4HNR1H2 | |
| SCHEMBL5991731 | 0.76 | THRA (0.56) | MEN1MITFALDH1A1GAAMAPT | |
| SCHEMBL5380053 | 0.76 | THRA (0.56) | MEN1MITFALDH1A1GAAMAPT | |
| SCHEMBL774501 | 0.75 | THRA (0.52) | MEN1MITFALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511113-B2 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-03-31 | — | — | US | disclosed |
| US-7511113-B2 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-03-31 | — | — | US | disclosed |
| US-7452959-B2 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-11-18 | — | — | US | disclosed |
| US-7452959-B2 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-11-18 | — | — | US | disclosed |