SCHEMBL774501

SCHEMBL774501

Oc1ccc(Oc2ccc(Oc3ccccc3)cc2)cc1Oc1ccc(Oc2ccc(Oc3ccc(Oc4ccccc4)cc3Oc3ccc(Oc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 4/20 0.52
THRB P10828 4/20 0.52
TTR P02766 3/20 0.50
LTA4H P09960 2/20 0.50
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
KDM4E B2RXH2 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MAOA P21397 1/20 0.45
TSHR P16473 1/20 0.44
F2 P00734 1/20 0.44
MEN1 O00255 1/20 0.42
MITF O75030 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
GFER P55789 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NLRP1 Q9C000 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5991731 0.94 THRA (0.56) THRATHRBTTRLTA4HNR1H2
SCHEMBL5380053 0.94 THRA (0.56) THRATHRBTTRLTA4HNR1H2
SCHEMBL11576951 0.86 LTA4H (0.55) TTRLTA4HNR1H2BAXMAOA
SCHEMBL9216280 0.84 MEN1 (0.54) LTA4HNR1H2BAXKDM4EMAOA
SCHEMBL4958922 0.82 TTR (0.65) TTRLTA4HNR1H2BAXTSHR
SCHEMBL8864080 0.81 LTA4H (0.55) TTRLTA4HNR1H2BAXKDM4E
SCHEMBL225442 0.79 CAMK2A (0.57) THRATHRBTTRLTA4HNR1H2
SCHEMBL5528855 0.78 LTA4H (0.60) TTRLTA4HNR1H2BAXMAOA
SCHEMBL11645394 0.78 LTA4H (0.67) LTA4HNR1H2BAXMAOATSHR
SCHEMBL11076245 0.78 TTR (0.62) TTRLTA4HNR1H2BAXKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9700851-B2 Phenol crosslink for sensor membrane WAVEFORM TECHNOLOGIES, INC. (US) 2017-07-11 US disclosed
US-20120067734-A1 PHENOL CROSSLINK FOR SENSOR MEMBRANE BAYER HEALTHCARE LLC (US) 2012-03-22 US disclosed