Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1743542 | 1.00 | SLC22A6 (0.55) | SLC22A6GABRR1LMNAMAPTAKR1B1 | |
| SCHEMBL8169661 | 0.79 | — | — | |
| SCHEMBL14539493 | 0.79 | — | — | |
| SCHEMBL6442999 | 0.79 | — | — | |
| SCHEMBL4541049 | 0.79 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL15627217 | 0.79 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6477452 | 0.79 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL15627216 | 0.79 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL15627215 | 0.79 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL356625 | 0.79 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631533-B1 | NOVEL PROCESS FOR STEREOSELECTIVE REDUCTION OF BETA-KETOESTERS | BIOCON LTD (IN) | 2009-03-11 | — | — | EP | disclosed |