SCHEMBL356625

SCHEMBL356625

C=CC(O)CC(O)CC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.52
GABRR1 P24046 2/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
BLM P54132 1/20 0.39
SLC6A3 Q01959 1/20 0.39
MEN1 O00255 1/20 0.39
CYP2D6 P10635 1/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
GPR84 Q9NQS5 4/20 0.36
HDAC2 Q92769 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
FOLH1 Q04609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15627215 1.00 SLC22A6 (0.52) SLC22A6GABRR1LMNAMAPTSLC6A2
SCHEMBL15627217 1.00 SLC22A6 (0.52) SLC22A6GABRR1LMNAMAPTSLC6A2
SCHEMBL15627216 1.00 SLC22A6 (0.52) SLC22A6GABRR1LMNAMAPTSLC6A2
SCHEMBL4541049 1.00 SLC22A6 (0.52) SLC22A6GABRR1LMNAMAPTSLC6A2
SCHEMBL6477452 1.00 SLC22A6 (0.52) SLC22A6GABRR1LMNAMAPTSLC6A2
SCHEMBL9730926 0.98 SLC22A6 (0.50) SLC22A6GABRR1LMNAMAPTSLC6A2
SCHEMBL1961185 0.98 SLC22A6 (0.50) SLC22A6GABRR1LMNAMAPTSLC6A2
SCHEMBL30645407 0.98 SLC22A6 (0.50) SLC22A6GABRR1LMNAMAPTSLC6A2
SCHEMBL22472213 0.84 SLC22A6 (0.38) SLC22A6GABRR1LMNAMAPTCYP2D6
SCHEMBL22472215 0.84 SLC22A6 (0.38) SLC22A6GABRR1LMNAMAPTCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117417677-A Water-based moisture-cured cold zinc acid and alkali resistant anticorrosive paint and application thereof 石家庄市鱼莎电力物资工程有限公司 2024-01-19 CN claimed
CN-114958134-A Water-based epoxy moisture-curing acid-and-alkali-resistant coating and preparation method thereof 石家庄市鱼莎电力物资工程有限公司 2022-08-30 CN claimed
CN-114076802-A Analysis method for quantitatively detecting nitrogen and oxygen impurities in pitavastatin calcium 徐州万邦金桥制药有限公司 2022-02-22 CN claimed
WO-2020197042-A1 METHOD FOR PREPARING ROSUVASTATIN CALCIUM SALT (주)헥사파마텍 2020-10-01 WO claimed
US-7692018-B2 Process for producing high purity 3,5-dihydroxy-6-heptenoic acid derivative NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-04-06 US claimed
EP-1667974-B1 PROCESS FOR PRODUCING HIGH PURITY 3,5-DIHYDROXY-6-HEPTENOIC ACID DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2009-07-29 EP claimed
EP-1968593-A2 PHARMACEUTICAL COMPOSITION COMPRISING (E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[METHYL(METHYLSULFONYL)AMINO]PYRIMIDIN-5-YL-(3R,5S)-3,5-DIHYDROXYHEPT-6-ENOIC ACID LEK Pharmaceuticals D.D. (SI) 2008-09-17 EP claimed
WO-2007071357-A2 PHARMACEUTICAL COMPOSITION COMPRISING (E) -7- [4- (4-FLUOROPHENYL) -6-ISOPROPYL-2- [METHYL (METHYLSULFONYL) AMINO] PYRIMIDIN-5 -YL- (3R, 5S) -3, 5-DIHYDR0XYHEPT-6-EN0IC ACID LEK PHARMACEUTICALS D.D. (SI) 2007-06-28 WO claimed
JP-2007507417-A 2007-03-29 JP claimed
US-20060229451-A1 Process for producing high purity 3,5-dihydroxy-6-heptenoic acid derivative NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-10-12 US claimed
EP-1667974-A1 PROCESS FOR PRODUCING HIGH PURITY 3,5-DIHYDROXY-6-HEPTENOIC ACID DERIVATIVE Nissan Chemical Industries, Ltd. (JP) 2006-06-14 EP claimed
WO-2005033083-A1 PROCESS FOR PRODUCING HIGH PURITY 3,5-DIHYDROXY-6-HEPTENOIC ACID DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-04-14 WO claimed
WO-2025090648-A1 METHODS AND COMPOSITIONS FOR INHIBITING METASTASIS OF SOLID TUMORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-05-01 WO disclosed
US-20240189221-A1 METHODS AND FORMULATIONS FOR TREATING VASCULAR DISEASE ENDOPERFUSION SOLUTIONS, LLC 2024-06-13 US disclosed
CN-117417677-A Water-based moisture-cured cold zinc acid and alkali resistant anticorrosive paint and application thereof 石家庄市鱼莎电力物资工程有限公司 2024-01-19 CN disclosed
CN-117050012-A Preparation method of 3, 5-dihydroxy-6-sodium heptenoate 江苏天晟药业股份有限公司 2023-11-14 CN disclosed
US-4808621-A Trans-6-[2-(N-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl]- or ethenyl]tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis WARNER-LAMBERT COMPANY (US) 1989-02-28 US disclosed
US-4751229-A Treating fungal infections with substituted-(6-(tetrahydro-4-hydroxy-2-oxo-2H-pyran-2-yl)ethyl)- or ethenyl)pyrazoles WARNER-LAMBERT COMPANY (US) 1988-06-14 US disclosed
EP-0252476-A2 Trans-6-[2-(N-heteroaryl-3,5-disubstituted) pyrazol-4-yl)-ethyl]- or ethenyl] tetrahydro-4-hydroxypyran-2-one-derivatives a process for their preparation and the use thereof WARNER-LAMBERT COMPANY (US) 1988-01-13 EP disclosed
WO-1984002903-A1 MEVALONOLACTONE ANALOGS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS SANDOZ AG (CH) 1984-08-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240189221-A1 METHODS AND FORMULATIONS FOR TREATING VASCULAR DISEASE LIPG, APOB, LIPA SLC22A6 597/4885GABRR1 2207/4885LMNA 1059/4885
US-20060229451-A1 Process for producing high purity 3,5-dihydroxy-6-heptenoic acid derivative ADH1A, ADH1C, DHCR7 SLC22A6 3327/4885GABRR1 1484/4885LMNA 2420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.