Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.67 |
| ▸ | NPC1 | O15118 | 11/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526236 | 0.84 | RAB9A (0.73) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL6125228 | 0.83 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL11783793 | 0.83 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL7217567 | 0.83 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL1713549 | 0.83 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL21047628 | 0.82 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL9571707 | 0.81 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL2202283 | 0.81 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL29561851 | 0.81 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL809829 | 0.80 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501421-B2 | Benzoxazole and benzothiazole derivatives as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2009-03-10 | — | — | US | disclosed |