SCHEMBL13903608

SCHEMBL13903608

CCCN(C)C1=NS(=O)(=O)c2cccc(Cl)c21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
KCNA3 P22001 4/20 0.36
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
HTT P42858 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
RET P07949 1/20 0.35
GRK5 P34947 1/20 0.35
TYRO3 Q06418 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
USP2 O75604 1/20 0.34
CXCR2 P25025 1/20 0.33
NPC1 O15118 1/20 0.33
GHSR Q92847 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13903587 0.89 KCNA3 (0.38) LMNAKCNA3ALDH1A1KDM4EHTT
SCHEMBL13903724 0.83 LMNA (0.39) LMNAKCNA3ALDH1A1KDM4EHTT
SCHEMBL13903613 0.82 MAOA (0.38) LMNAKCNA3ALDH1A1KDM4EHTT
SCHEMBL4125659 0.82 RET (0.34) LMNAKCNA3ALDH1A1KDM4EHTT
SCHEMBL13903578 0.82 RET (0.40) LMNAKCNA3ALDH1A1KDM4EHTT
SCHEMBL13903579 0.81 HTT (0.43) KCNA3ALDH1A1KDM4EHTTMEN1
SCHEMBL13903615 0.81 LMNA (0.43) LMNAKCNA3ALDH1A1KDM4EHTT
SCHEMBL13903683 0.81 LMNA (0.33) LMNAKCNA3ALDH1A1KDM4EHTT
SCHEMBL13903603 0.81 KCNA3 (0.37) LMNAKCNA3ALDH1A1KDM4EHTT
SCHEMBL13903677 0.80 RET (0.36) LMNAKCNA3ALDH1A1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090069317-A1 Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives BASF SE (DE) 2009-03-12 US disclosed
US-20090069317-A1 Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives BASF SE (DE) 2009-03-12 US disclosed
WO-2007057407-A2 INSECTICIDAL METHODS USING 3-AMINO-1,2-BENZISOTHIAZOLE DERIVATIVES BASF SE (DE) 2007-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090069317-A1 Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives AAAS, API5, ATL3 LMNA 3264/4885KCNA3 850/4885ALDH1A1 731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.