Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1319104 | 0.90 | RECQL (0.69) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1319752 | 0.84 | RECQL (0.60) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2055420 | 0.84 | RECQL (0.60) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2055417 | 0.84 | RECQL (0.60) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2055434 | 0.81 | ACLY (0.58) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2055427 | 0.81 | ACLY (0.58) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL164503 | 0.80 | RECQL (0.76) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2098718 | 0.80 | RECQL (0.55) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1110445 | 0.79 | KEAP1 (0.49) | RECQLKEAP1ACLYHKDC1NFE2L2 | |
| SCHEMBL2055418 | 0.79 | RECQL (0.69) | RECQLKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009030715-A1 | ARYLSULFONYLAMINOMETHYLPHOSPHONIC ACID DERIVATIVES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |