Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.49 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394218 | 0.86 | RAB9A (0.63) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL3956042 | 0.83 | RAB9A (0.57) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL2354124 | 0.82 | RAB9A (0.61) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL2346273 | 0.82 | RAB9A (0.61) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL4240335 | 0.81 | MAPT (0.55) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL2348925 | 0.80 | RAB9A (0.56) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL2347557 | 0.79 | MAPK1 (0.55) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL2350379 | 0.78 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL12394235 | 0.77 | RAB9A (0.62) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL12394223 | 0.76 | RAB9A (0.70) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034390-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |