Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956042 | 0.88 | RAB9A (0.57) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL2344153 | 0.85 | MAPT (0.63) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL3962780 | 0.83 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL13907630 | 0.82 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL13907801 | 0.81 | ALDH1A1 (0.62) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL2346099 | 0.80 | MAPK14 (0.60) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL2352743 | 0.79 | MAPT (0.58) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL2342385 | 0.79 | PKM (0.61) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL2352480 | 0.78 | PKM (0.70) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL2350760 | 0.78 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034390-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009034390-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |