Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13908363 | 0.92 | KMT2A (0.51) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL27759421 | 0.92 | KMT2A (0.51) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL23039956 | 0.83 | MEN1 (0.48) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL23058774 | 0.83 | MEN1 (0.48) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL23039954 | 0.83 | MEN1 (0.48) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL13733686 | 0.83 | MEN1 (0.48) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL13733682 | 0.82 | MEN1 (0.47) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL13733690 | 0.82 | MEN1 (0.47) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL30521710 | 0.82 | MEN1 (0.47) | KMT2AMEN1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL23058787 | 0.81 | MEN1 (0.46) | KMT2AMEN1L3MBTL1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4408850-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2024-08-07 | — | — | EP | disclosed |
| EP-4408849-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023055912-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2023-04-06 | — | — | WO | disclosed |
| WO-2023055920-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2023-04-06 | — | — | WO | disclosed |