Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | GPR4 | P46093 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13908694 | 0.79 | VDR (0.40) | MEN1KMT2A | |
| SCHEMBL13963650 | 0.65 | HDAC3 (0.34) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL14434406 | 0.64 | MEN1 (0.41) | ESRRGMEN1KMT2A | |
| SCHEMBL19649169 | 0.61 | HDAC6 (0.36) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL15587287 | 0.61 | CHRM2 (0.41) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL13253683 | 0.61 | PLK1 (0.50) | HDAC1HDAC6HDAC8HDAC2ESRRG | |
| SCHEMBL27499157 | 0.60 | CA12 (0.57) | APPMEN1KMT2A | |
| SCHEMBL7718268 | 0.60 | APP (0.42) | APPMEN1KMT2A | |
| SCHEMBL9915630 | 0.60 | APP (0.42) | APPMEN1KMT2A | |
| SCHEMBL9915609 | 0.60 | APP (0.42) | APPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037348-A1 | INDOLINIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISNG THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |