Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915630 | 1.00 | APP (0.42) | APPALDH1A1RELAALDH3A1ALDH1A3 | |
| SCHEMBL7718268 | 1.00 | APP (0.42) | APPALDH1A1RELAALDH3A1ALDH1A3 | |
| SCHEMBL2604913 | 0.92 | RELA (0.52) | ALDH1A1RELAKMT2AMEN1MAPT | |
| SCHEMBL3025045 | 0.90 | ALDH1A1 (0.55) | APPALDH1A1ALDH3A1ALDH1A3GAA | |
| SCHEMBL9915872 | 0.90 | APP (0.48) | APPALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3025048 | 0.90 | ALDH1A1 (0.55) | APPALDH1A1ALDH3A1ALDH1A3GAA | |
| SCHEMBL12476438 | 0.89 | NPC1 (0.55) | APPALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL9915607 | 0.87 | CHRM2 (0.53) | APPALDH1A1ALDH3A1ALDH1A3GAA | |
| SCHEMBL19003828 | 0.86 | CHRM2 (0.49) | APPALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL15587307 | 0.86 | ALDH1A1 (0.57) | ALDH1A1GAAKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |