Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25907749 | 0.81 | TRPA1 (0.54) | TRPA1TRPM8EPHX1 | |
| SCHEMBL25907747 | 0.81 | TRPA1 (0.54) | TRPA1TRPM8EPHX1 | |
| SCHEMBL25907743 | 0.81 | TRPA1 (0.54) | TRPA1TRPM8EPHX1 | |
| SCHEMBL25908020 | 0.81 | TRPA1 (0.54) | TRPA1TRPM8EPHX1 | |
| SCHEMBL12166520 | 0.79 | TRPA1 (0.52) | TRPA1TRPM8EPHX1 | |
| SCHEMBL13712036 | 0.73 | — | — | |
| SCHEMBL16743130 | 0.70 | TRPA1 (0.46) | TRPA1TRPM8EPHX1 | |
| SCHEMBL853466 | 0.70 | TRPA1 (0.46) | TRPA1TRPM8EPHX1 | |
| SCHEMBL875598 | 0.70 | TRPA1 (0.42) | TRPA1TRPM8EPHX1 | |
| SCHEMBL20824753 | 0.70 | TRPA1 (0.47) | TRPA1TRPM8EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501535-B2 | Chemical synthons and intermediates | PURDUE RESEARCH FOUNDATION (US) | 2009-03-10 | — | — | US | disclosed |