Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25907747 | 1.00 | TRPA1 (0.54) | TRPA1TRPM8EPHX1CA1CA2 | |
| SCHEMBL25907743 | 1.00 | TRPA1 (0.54) | TRPA1TRPM8EPHX1CA1CA2 | |
| SCHEMBL25908020 | 1.00 | TRPA1 (0.54) | TRPA1TRPM8EPHX1CA1CA2 | |
| SCHEMBL12166520 | 0.92 | TRPA1 (0.52) | TRPA1TRPM8EPHX1 | |
| SCHEMBL16743130 | 0.87 | TRPA1 (0.46) | TRPA1TRPM8EPHX1CA1CA2 | |
| SCHEMBL853466 | 0.87 | TRPA1 (0.46) | TRPA1TRPM8EPHX1CA1CA2 | |
| SCHEMBL18611340 | 0.81 | TRPA1 (0.47) | TRPA1TRPM8EPHX1 | |
| SCHEMBL13909489 | 0.81 | TRPA1 (0.47) | TRPA1TRPM8EPHX1 | |
| SCHEMBL20824753 | 0.81 | TRPA1 (0.47) | TRPA1TRPM8EPHX1 | |
| SCHEMBL13712036 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242526-A1 | Deuterated Pyridopyrimidinones And Their Use As Highly Selective Cyclin-Dependent Kinase 2 Inhibitors | ZENTAUR THERAPEUTICS INTERNATIONAL LIMITED (CN) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242526-A1 | Deuterated Pyridopyrimidinones And Their Use As Highly Selective Cyclin-Dependent Kinase 2 Inhibitors | CDK2, CDK4, CCNI | TRPA1 4820/4885TRPM8 4669/4885EPHX1 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.