Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 9/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | RAD1 | O60671 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | BCL2 | P10415 | 1/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.77 |
| ▸ | BID | P55957 | 1/20 | 0.77 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.77 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13912138 | 0.98 | BCL2A1 (0.75) | BCL2A1ALDH1A1RAD51MAPTRAD1 | |
| SCHEMBL4257590 | 0.87 | BCL2A1 (1.00) | BCL2A1ALDH1A1RAD51MAPTRAD1 | |
| SCHEMBL13186471 | 0.87 | RAD51 (1.00) | BCL2A1ALDH1A1RAD51MAPTRAD1 | |
| SCHEMBL13912158 | 0.84 | BCL2A1 (1.00) | BCL2A1ALDH1A1RAD51MAPTRAD1 | |
| SCHEMBL13912163 | 0.83 | BCL2A1 (0.71) | BCL2A1ALDH1A1RAD51MAPTRAD1 | |
| SCHEMBL13912155 | 0.82 | BCL2A1 (1.00) | BCL2A1ALDH1A1RAD51MAPTRAD1 | |
| SCHEMBL13912162 | 0.81 | BCL2A1 (1.00) | BCL2A1ALDH1A1RAD51MAPTRAD1 | |
| SCHEMBL15347242 | 0.80 | L3MBTL1 (0.97) | ALDH1A1RAD51MAPTALOX12L3MBTL1 | |
| SCHEMBL10834724 | 0.80 | BCL2A1 (0.69) | BCL2A1ALDH1A1RAD51MAPTRAD1 | |
| SCHEMBL17208335 | 0.80 | RAD51 (0.64) | BCL2A1ALDH1A1RAD51MAPTRAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069324-A1 | CHEMICAL INHIBITORS OF BFL-1 AND RELATED METHODS | THE BURNHAM INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
| US-20090069324-A1 | CHEMICAL INHIBITORS OF BFL-1 AND RELATED METHODS | THE BURNHAM INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
| WO-2008157003-A2 | CHEMICAL INHIBITORS OF BFL-1 AND RELATED METHODS | THE BURNHAM INSTITUTE (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069324-A1 | CHEMICAL INHIBITORS OF BFL-1 AND RELATED METHODS | TMBIM6, BCL2L1, BCL2L11 | BCL2A1 11/4885ALDH1A1 2702/4885RAD51 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.