Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 9/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | RECQL | P46063 | 5/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MTOR | P42345 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | THPO | P40225 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637503 | 0.91 | SHBG (0.43) | SHBGADRB2PTGS2OPRK1SLC6A3 | |
| SCHEMBL881176 | 0.81 | SHBG (0.44) | SHBGADRB2PTGS2KDM4ETDP1 | |
| SCHEMBL13984318 | 0.77 | HSD17B10 (0.49) | SHBGADRB2PTGS2OPRK1SLC6A3 | |
| SCHEMBL13637508 | 0.76 | SHBG (0.45) | SHBGADRB2PTGS2KDM4ETDP1 | |
| SCHEMBL19425427 | 0.75 | TDP1 (0.50) | SHBGADRB2PTGS2OPRK1SLC6A3 | |
| SCHEMBL13912410 | 0.75 | SHBG (0.64) | SHBGADRB2PTGS2OPRK1SLC6A3 | |
| SCHEMBL21851714 | 0.75 | TDP1 (0.56) | SHBGADRB2PTGS2OPRK1SLC6A3 | |
| SCHEMBL26015539 | 0.70 | SHBG (0.66) | SHBGADRB2PTGS2OPRK1SLC6A3 | |
| SCHEMBL19154003 | 0.70 | KDM4E (0.51) | SHBGADRB2PTGS2OPRK1SLC6A3 | |
| SCHEMBL107203 | 0.69 | TDP1 (0.59) | ADRB2PTGS2KDM4ETDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076241-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | NERITES CORPORATION | 2009-03-19 | — | — | US | disclosed |