Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | RECQL | P46063 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | BLM | P54132 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MTOR | P42345 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | APEX1 | P27695 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637508 | 0.82 | SHBG (0.45) | SHBGTDP1MAPTKDM4ERECQL | |
| SCHEMBL13912464 | 0.81 | SHBG (0.46) | SHBGTDP1MAPTKDM4ERECQL | |
| SCHEMBL13912410 | 0.78 | SHBG (0.64) | SHBGTDP1MAPTKDM4ERECQL | |
| SCHEMBL12248156 | 0.76 | SHBG (0.49) | SHBGTDP1MAPTKDM4ERECQL | |
| SCHEMBL13637503 | 0.75 | SHBG (0.43) | SHBGTDP1MAPTKDM4ERECQL | |
| SCHEMBL107203 | 0.74 | TDP1 (0.59) | TDP1MAPTKDM4ERECQLKMT2A | |
| SCHEMBL13912408 | 0.73 | ALOX15 (0.59) | SHBGTDP1MAPTKDM4ERECQL | |
| SCHEMBL10582745 | 0.72 | TDP1 (0.57) | TDP1MAPTKDM4ERECQLKMT2A | |
| SCHEMBL11061261 | 0.72 | SHBG (0.49) | SHBGTDP1MAPTKDM4ERECQL | |
| SCHEMBL19495182 | 0.72 | SHBG (0.35) | SHBGTDP1MAPTKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030413-B2 | Biomimetic compounds and synthetic methods therefor | KNC NER ACQUISITION SUB, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-20100197868-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | NERITES CORPORATION (US) | 2010-08-05 | — | — | US | disclosed |