Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | BCR | P11274 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13366160 | 0.84 | ABL1 (0.47) | ABL1ABCB1BCRCA12CA1 | |
| SCHEMBL13366078 | 0.84 | ABL1 (0.47) | ABL1ABCB1BCRPPARAPPARG | |
| SCHEMBL6807218 | 0.83 | ABL1 (0.55) | ABL1ABCB1BCRCA12CA1 | |
| SCHEMBL11996556 | 0.82 | ABCB1 (0.50) | ABL1ABCB1BCRPPARAPPARG | |
| SCHEMBL12715050 | 0.81 | ABL1 (0.79) | ABL1ABCB1BCRCA12CA1 | |
| SCHEMBL4188809 | 0.81 | SMN1; SMN2 (0.50) | ABL1ABCB1BCRCA12CA1 | |
| SCHEMBL27613425 | 0.80 | ABL1 (0.51) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL13913540 | 0.80 | CYP1A2 (0.50) | MEN1KMT2AMAOBL3MBTL1 | |
| SCHEMBL13700675 | 0.80 | GABRA1 (0.44) | ABL1ABCB1BCRPPARAPPARG | |
| SCHEMBL22589013 | 0.79 | CA12 (0.59) | CA12CA1CA2CA9PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |