Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | BCR | P11274 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1210873 | 0.84 | ALDH1A1 (0.41) | ABL1ABCB1BCRMAPTRAB9A | |
| SCHEMBL13913541 | 0.83 | ABL1 (0.56) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL6258936 | 0.80 | MAPT (0.48) | PTPN1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12715050 | 0.80 | ABL1 (0.79) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL27613425 | 0.79 | ABL1 (0.51) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL11096260 | 0.78 | ABL1 (0.76) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL11996556 | 0.77 | ABCB1 (0.50) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL8972805 | 0.77 | ABL1 (0.50) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL31376566 | 0.77 | ABL1 (0.50) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL3253571 | 0.76 | ABL1 (0.49) | ABL1ABCB1BCRHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040018598-A1 | Bio-intermediates for use in the chemical synthesis of polyketides | SANTI DANIEL (US) | 2004-01-29 | — | — | US | disclosed |
| EP-1307579-A2 | BIO-INTERMEDIATES FOR USE IN THE CHEMICAL SYNTHESIS OF POLYKETIDES | Kosan Biosciences, Inc. (US) | 2003-05-07 | — | — | EP | disclosed |
| US-20020052028-A1 | Bio-intermediates for use in the chemical synthesis of polyketides | KOSAN BIOSCIENCES, INC. | 2002-05-02 | — | — | US | disclosed |
| WO-2002012534-A2 | BIO-INTERMEDIATES FOR USE IN THE CHEMICAL SYNTHESIS OF POLYKETIDES | KOSAN BIOSCIENCES, INC. (US) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040018598-A1 | Bio-intermediates for use in the chemical synthesis of polyketides | DHPS, FDFT1, COASY | ABL1 4748/4885ABCB1 1736/4885BCR 2016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.