Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD5 | P21918 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28945714 | 0.82 | TRPA1 (0.58) | HIF1AHSD17B10CYP3A4NFKB1CYP2D6 | |
| SCHEMBL108110 | 0.82 | CA1 (0.61) | HIF1AHSD17B10CYP3A4NFKB1CYP2D6 | |
| SCHEMBL107974 | 0.79 | TRPA1 (0.54) | HIF1AHSD17B10CYP3A4NFKB1CYP2D6 | |
| SCHEMBL67764 | 0.79 | HIF1A (0.65) | HIF1AHSD17B10CYP3A4NFKB1CYP2D6 | |
| SCHEMBL30141595 | 0.79 | HIF1A (0.65) | HIF1AHSD17B10CYP3A4NFKB1CYP2D6 | |
| Bromide SCHEMBL20854749 | 0.77 | KDM4E (0.66) | HIF1AHSD17B10CYP3A4NFKB1CYP2D6 | |
| SCHEMBL12980193 | 0.75 | TRPA1 (0.54) | HIF1AHSD17B10CYP3A4NFKB1CYP2D6 | |
| SCHEMBL13886168 | 0.74 | DRD1 (0.59) | HIF1AHSD17B10CYP3A4NFKB1CYP2D6 | |
| SCHEMBL8052751 | 0.74 | KDM4E (0.52) | HIF1AHSD17B10CYP3A4NFKB1CYP2D6 | |
| SCHEMBL14067081 | 0.73 | TRPA1 (0.52) | HIF1AHSD17B10CYP3A4NFKB1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754133-B2 | Compounds, compositions and methods for the treatment of inflammatory diseases | PROTEOTECH, INC. (US) | 2014-06-17 | — | — | US | claimed |
| US-20120058998-A1 | Compounds, Compositions and Methods for the Treatment of Inflammatory Diseases | PROTAMED, INC. | 2012-03-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058998-A1 | Compounds, Compositions and Methods for the Treatment of Inflammatory Diseases | NR1H2, NR1H3, MSR1 | HIF1A 571/4885HSD17B10 368/4885CYP3A4 985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.