Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | DRD2 | P14416 | 3/20 | 0.65 |
| ▸ | DRD1 | P21728 | 3/20 | 0.65 |
| ▸ | DRD4 | P21917 | 3/20 | 0.65 |
| ▸ | DRD5 | P21918 | 3/20 | 0.65 |
| ▸ | DRD3 | P35462 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.59 |
| ▸ | IGF1R | P08069 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30141595 | 1.00 | HIF1A (0.65) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| Bromide SCHEMBL20854749 | 0.98 | KDM4E (0.66) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL10301530 | 0.88 | HIF1A (0.65) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL27269175 | 0.84 | HIF1A (0.61) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL16449326 | 0.84 | DRD2 (0.61) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL5983338 | 0.84 | HRH3 (0.50) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL7319293 | 0.84 | HIF1A (0.61) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL29204036 | 0.82 | TAAR1 (0.55) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL13886168 | 0.82 | DRD1 (0.59) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL11279264 | 0.81 | HRH3 (0.51) | HIF1AHSD17B10DRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473454-B2 | Water-based extrusion primer for polyethylene | HENKEL AG & CO. KGAA (DE) | 2025-11-18 | — | — | US | disclosed |
| US-12227668-B2 | Use of preformed reaction products of catechol compounds and functionalized co-reactant compounds to reduce oxidation of bare metal surfaces | HENKEL AG & CO. KGAA (DE) | 2025-02-18 | — | — | US | disclosed |
| EP-3559311-B1 | USE OF PREFORMED REACTION PRODUCTS OF CATECHOL COMPOUNDS AND FUNCTIONALIZED CO-REACTANT COMPOUNDS TO REDUCE OXIDATION OF BARE METAL SURFACES | HENKEL AG & CO KGAA (DE) | 2024-12-11 | — | — | EP | disclosed |
| EP-3559312-B1 | REACTION PRODUCTS OF CATECHOL COMPOUNDS AND FUNCTIONALIZED CO-REACTANT COMPOUNDS FOR METAL PRETREATMENT APPLICATIONS | HENKEL AG & CO KGAA (DE) | 2024-04-24 | — | — | EP | disclosed |
| EP-3558667-B1 | TREATMENT OF CONVERSION-COATED METAL SUBSTRATES WITH PREFORMED REACTION PRODUCTS OF CATECHOL COMPOUNDS AND FUNCTIONALIZED CO-REACTANT COMPOUNDS | HENKEL AG & CO KGAA (DE) | 2024-03-20 | — | — | EP | disclosed |
| US-11891534-B2 | Treatment of conversion-coated metal substrates with preformed reaction products of catechol compounds and functionalized co-reactant compounds | HENKEL AG & CO. KGAA (DE) | 2024-02-06 | — | — | US | disclosed |
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |
| US-11407921-B2 | Reaction products of catechol compounds and functionalized co-reactant compounds for metal pretreatment applications | HENKEL AG & CO. KGAA (DE) | 2022-08-09 | — | — | US | disclosed |
| EP-3699247-B1 | WATER-BASED EXTRUSION PRIMER FOR POLYETHYLENE | HENKEL AG & CO KGAA (DE) | 2022-02-09 | — | — | EP | disclosed |
| US-20210371699-A1 | WATER-BASED EXTRUSION PRIMER FOR POLYETHYLENE | HENKEL AG & CO. KGAA (DE) | 2021-12-02 | — | — | US | disclosed |
| US-4918074-A | CALCIUM ANTAGONISTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0259480-A4 | SUBSTITUTED 2-AMINOTETRALINS. | NELSON RES & DEV COMPANY (US) | 1988-07-25 | — | — | EP | disclosed |
| US-4743618-A | DOPAMINE RECEPTOR ANTAGONISTS, GLAUCOMA TREATMENT | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0259480-A1 | SUBSTITUTED 2-AMINOTETRALINS | Whitby Research Incorporated (US) | 1988-03-16 | — | — | EP | disclosed |
| EP-0257285-A2 | Method and compositions for reducing the intraocular pressure of mammals | Whitby Research Incorporated (US) | 1988-03-02 | — | — | EP | disclosed |
| EP-0254989-A2 | Substituted 2-Aminotetralins | Whitby Research Incorporated (US) | 1988-02-03 | — | — | EP | disclosed |
| US-4722933-A | GLAUCOMA TREATMENT | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1988-02-02 | — | — | US | disclosed |
| WO-1987005602-A1 | SUBSTITUTED 2-AMINOTETRALINS | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1987-09-24 | — | — | WO | disclosed |
| EP-0230629-A2 | 2-Propylamino-tetralin derivatives for reducing intraocular pressure | Whitby Research Incorporated (US) | 1987-08-05 | — | — | EP | disclosed |
| US-4657925-A | Method and compositions for reducing the intraocular pressure of mammals | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1987-04-14 | — | — | US | disclosed |