Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3165778 | 0.98 | ALDH1A1 (0.49) | ALDH1A1ATMFAAHMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3175886 | 0.97 | ALDH1A1 (0.48) | ALDH1A1ATMFAAHMEN1KMT2A | |
| SCHEMBL3156207 | 0.94 | ALDH1A1 (0.48) | ALDH1A1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3163746 | 0.92 | ALDH1A1 (0.50) | ALDH1A1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3165011 | 0.91 | MEN1 (0.46) | ALDH1A1FAAHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3162253 | 0.90 | ALDH1A1 (0.52) | ALDH1A1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3171582 | 0.89 | MEN1 (0.47) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL3170797 | 0.88 | ACHE (0.46) | ALDH1A1FAAHGAAMAPTSIGMAR1 | |
| SCHEMBL3156798 | 0.88 | MEN1 (0.48) | ALDH1A1FAAHMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3169892 | 0.88 | ACHE (0.46) | ALDH1A1FAAHGAAMAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501407-B2 | Pyrimidine A2B selective antagonist compounds, their synthesis and use | OSI PHARMACEUTICALS, INC. (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501407-B2 | Pyrimidine A2B selective antagonist compounds, their synthesis and use | OSI PHARMACEUTICALS, INC. (US) | 2009-03-10 | — | — | US | disclosed |