Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12396300 | 0.82 | ALDH1A1 (0.40) | ALDH1A1HTTTSHRPOLBKDM4E | |
| SCHEMBL12705542 | 0.79 | SMYD3 (0.39) | ALDH1A1HTTTSHRPOLBKDM4E | |
| SCHEMBL3771260 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL3644549 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL12396230 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL2159702 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL8274289 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL13920578 | 0.76 | KMT2A (0.34) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13920579 | 0.76 | KMT2A (0.34) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL13920585 | 0.74 | MMP2 (0.39) | ALDH1A1MAPTMEN1KMT2ASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511062-B2 | Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors | SCHERING CORPORATION (US) | 2009-03-31 | — | — | US | disclosed |