Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13920584 | 1.00 | MMP2 (0.46) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL14367090 | 0.85 | MMP2 (0.63) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL14278562 | 0.78 | MMP2 (0.56) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL13920579 | 0.76 | KMT2A (0.34) | FKBP1A | |
| SCHEMBL13920578 | 0.76 | KMT2A (0.34) | FKBP1A | |
| SCHEMBL15221388 | 0.76 | MMP2 (0.45) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL13920585 | 0.75 | MMP2 (0.39) | MMP2ANPEPFKBP1A | |
| SCHEMBL13920586 | 0.75 | MMP2 (0.39) | MMP2ANPEPFKBP1A | |
| SCHEMBL15221350 | 0.74 | MMP2 (0.43) | MMP2ANPEPDPP7DPP8DPP9 | |
| SCHEMBL15221374 | 0.74 | MMP2 (0.43) | MMP2ANPEPDPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511062-B2 | Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors | SCHERING CORPORATION (US) | 2009-03-31 | — | — | US | disclosed |