Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13920585 | 1.00 | MMP2 (0.39) | MMP2ANPEPKMT2AMEN1ALDH1A1 | |
| SCHEMBL13920578 | 0.83 | KMT2A (0.34) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL13920579 | 0.83 | KMT2A (0.34) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL14288714 | 0.78 | MMP2 (0.42) | MMP2ANPEPKMT2AMEN1ALDH1A1 | |
| SCHEMBL13920584 | 0.75 | MMP2 (0.46) | MMP2ANPEPFKBP1A | |
| SCHEMBL13920587 | 0.75 | MMP2 (0.46) | MMP2ANPEPFKBP1A | |
| SCHEMBL13604536 | 0.75 | MAPT (0.37) | KMT2AMEN1ALDH1A1MAPTFKBP1A | |
| SCHEMBL13920580 | 0.74 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1MAPTSMYD3 | |
| SCHEMBL12705543 | 0.74 | ANPEP (0.50) | MMP2ANPEPKMT2AMEN1ALDH1A1 | |
| SCHEMBL15221357 | 0.72 | MMP2 (0.38) | MMP2ANPEPKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511062-B2 | Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors | SCHERING CORPORATION (US) | 2009-03-31 | — | — | US | disclosed |