Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.67 |
| ▸ | CTSK | P43235 | 3/20 | 0.67 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13921008 | 1.00 | CTSS (0.67) | CTSSCTSKCA2PSENENCAPN1 | |
| SCHEMBL28969873 | 0.87 | CTSS (0.69) | CTSSCTSKCA2PSENENCAPN1 | |
| SCHEMBL13921027 | 0.87 | CTSK (0.65) | CTSSCTSKCA2PSENENCAPN1 | |
| SCHEMBL13921005 | 0.87 | CTSK (0.65) | CTSSCTSKCA2PSENENCAPN1 | |
| SCHEMBL13934344 | 0.86 | CTSK (0.67) | CTSSCTSKCA2PSENENCAPN1 | |
| SCHEMBL26818255 | 0.86 | CTSS (0.67) | CTSSCTSKCA2PSENENCAPN1 | |
| SCHEMBL13934284 | 0.86 | CTSK (0.67) | CTSSCTSKCA2PSENENCAPN1 | |
| SCHEMBL16909078 | 0.85 | CTSS (0.70) | CTSSCTSKCA2PSENENCAPN1 | |
| SCHEMBL16921308 | 0.85 | CTSS (0.66) | CTSSCTSKCA2PSENENCAPN1 | |
| SCHEMBL16921307 | 0.85 | CTSS (0.70) | CTSSCTSKCA2PSENENCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498353-B2 | Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2009-03-03 | — | — | US | disclosed |