SCHEMBL13921979

SCHEMBL13921979

C=C(C)C(=O)Nc1ccc(S(=O)(=O)NC(=O)CC)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.56
ATM Q13315 1/20 0.53
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
SCN3A Q9NY46 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
POLB P06746 1/20 0.47
ALDH1A1 P00352 4/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 1/20 0.46
MMP2 P08253 2/20 0.45
MMP1 P03956 1/20 0.45
MMP9 P14780 1/20 0.45
MMP8 P22894 1/20 0.45
MMP13 P45452 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9887824 0.85 SMN1; SMN2 (0.58) SMN1; SMN2CA1CA2L3MBTL1SCN3A
SCHEMBL393581 0.82 LMNA (0.59) SMN1; SMN2CA1CA2CA12CA9
SCHEMBL394378 0.80 RXFP1 (0.54) SMN1; SMN2CA1CA2CA12CA9
SCHEMBL11849624 0.80 RXFP1 (0.54) SMN1; SMN2ATMCA1CA2CA12
SCHEMBL398015 0.80 POLB (0.61) SMN1; SMN2CA1CA2CA12CA9
SCHEMBL16809952 0.79 CA1 (0.49) SMN1; SMN2CA1CA2CA12CA9
SCHEMBL7607384 0.78 PKM (0.59) ATMCA1CA2CA12CA9
SCHEMBL23196556 0.78 KMT2A (0.57) CA1CA2CA12CA9L3MBTL1
SCHEMBL13921976 0.78 KMT2A (0.52) CA1CA2CA12CA9RXFP1
SCHEMBL396210 0.78 SMN1; SMN2 (0.56) SMN1; SMN2CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507525-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-7279539-B2 Alkali-soluble polymer and polymerizable composition thereof FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed