Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20254428 | 0.86 | MEN1 (0.78) | ADRA1AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL4313455 | 0.85 | ADRA1A (0.69) | ADRA1AMEN1CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL30658979 | 0.84 | MEN1 (0.76) | ADRA1AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL4350904 | 0.82 | CYP2J2 (0.69) | ADRA1AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL7393089 | 0.80 | ADRA1D (0.62) | ADRA1AKCNH2DRD2ADRA1DADRA1B | |
| SCHEMBL13925153 | 0.79 | CYP2J2 (0.56) | ADRA1AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL12022081 | 0.79 | CYP2J2 (0.59) | ADRA1AMEN1CHRM2HTR1AADRA2A | |
| Fumaric Acid SCHEMBL10768049 | 0.76 | CYP2J2 (0.65) | ADRA1AMEN1CHRM2HTR1AADRA2A | |
| Fumaric Acid SCHEMBL10768052 | 0.76 | CYP2J2 (0.65) | ADRA1AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL12142514 | 0.76 | CYP2J2 (0.53) | ADRA1AMEN1CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498443-B2 | Process for production of carebastine | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-03-03 | — | — | US | disclosed |