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SCHEMBL13927002

SCHEMBL13927002

C=Cc1ccc(C(=O)Nc2ccc(C(c3ccc(NC(=O)c4cc(C=C)ccc4C(=O)O)cc3)(C(F)(F)F)C(F)(F)F)cc2)c(C(=O)O)c1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SORT1 Q99523 11/20 0.45
▸ ALDH1A1 P00352 1/20 0.40
▸ F2 P00734 1/20 0.40
▸ F10 P00742 1/20 0.40
▸ GRIK1 P39086 1/20 0.37
▸ TGM2 P21980 1/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13927003 0.98 F2 (0.41) SORT1ALDH1A1F2F10GRIK1
SCHEMBL13927023 0.94 MEN1 (0.47) SORT1ALDH1A1
SCHEMBL13927019 0.91 MEN1 (0.46) SORT1ALDH1A1
SCHEMBL13927001 0.91 SORT1 (0.42) SORT1ALDH1A1F2F10GRIK1
SCHEMBL13927016 0.91 MEN1 (0.46) ALDH1A1
SCHEMBL13926964 0.88 ALDH1A1 (0.51) SORT1ALDH1A1F2F10
SCHEMBL13926997 0.86 SORT1 (0.44) SORT1ALDH1A1F2F10
SCHEMBL13926965 0.85 ALDH1A1 (0.50) ALDH1A1F2F10
SCHEMBL13926963 0.85 ALDH1A1 (0.50) SORT1ALDH1A1F2F10
SCHEMBL13926999 0.83 F2 (0.45) SORT1ALDH1A1F2F10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090048421-A1 FILM FORMING COMPOSITION, FILM, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2009-02-19 — — US disclosed
US-20090048421-A1 FILM FORMING COMPOSITION, FILM, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2009-02-19 — — US disclosed
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