Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 18/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13928756 | 0.90 | CCR5 (0.37) | CCR5 | |
| SCHEMBL4209657 | 0.84 | KCNH2 (0.53) | CCR5KCNH2DRD2HTR2AHTR2C | |
| SCHEMBL4207407 | 0.82 | OPRM1 (0.50) | CCR5KCNH2DRD2SIGMAR1 | |
| SCHEMBL13928769 | 0.82 | CCR5 (0.41) | CCR5KCNH2HTR2AHTR2C | |
| SCHEMBL4210046 | 0.81 | CCR5 (0.46) | CCR5 | |
| SCHEMBL4215524 | 0.81 | HTT (0.45) | DRD2 | |
| SCHEMBL4205766 | 0.80 | CCR5 (0.44) | CCR5 | |
| SCHEMBL4215525 | 0.79 | CCR5 (0.41) | CCR5KCNH2 | |
| SCHEMBL4208066 | 0.79 | CCR5 (0.38) | CCR5 | |
| SCHEMBL4202240 | 0.78 | CCR5 (0.37) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |