Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13928766 | 0.85 | HPGD (0.43) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4211853 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4208589 | 0.85 | HPGD (0.45) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13928715 | 0.84 | DRD4 (0.43) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13928752 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13928749 | 0.83 | CCR5 (0.43) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13928763 | 0.82 | HPGD (0.46) | POLBCYP3A4CYP2C9HPGDMEN1 | |
| SCHEMBL4218054 | 0.81 | MCHR1 (0.52) | HPGDALDH1A1 | |
| SCHEMBL4207381 | 0.81 | HPGD (0.45) | HPGDDRD2DRD4 | |
| SCHEMBL4204597 | 0.78 | HPGD (0.42) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |