Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13928770 | 0.90 | ALDH1A1 (0.54) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13928761 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4211853 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13928725 | 0.84 | NPSR1 (0.43) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4215450 | 0.84 | SSTR4 (0.38) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13928754 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13928753 | 0.82 | SSTR4 (0.38) | POLBCYP3A4CYP2C9DRD4DRD2 | |
| SCHEMBL4207043 | 0.82 | MCHR1 (0.52) | SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL4207301 | 0.81 | DRD2 (0.39) | DRD4DRD2 | |
| SCHEMBL5882127 | 0.78 | SSTR4 (0.38) | CYP3A4CYP2C9ALDH1A1DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |