Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521863 | 0.96 | KCNA3 (0.59) | DRD2DRD4DRD3FFAR1KCNA3 | |
| SCHEMBL14463902 | 0.89 | FFAR1 (0.62) | DRD2DRD4DRD3FFAR1KCNA3 | |
| SCHEMBL8422540 | 0.87 | KCNA3 (0.61) | DRD2DRD4DRD3FFAR1KCNA3 | |
| SCHEMBL10733620 | 0.87 | FFAR1 (0.56) | DRD2DRD4DRD3FFAR1KCNA3 | |
| SCHEMBL8767683 | 0.85 | LTA4H (0.62) | DRD2DRD4DRD3FFAR1KCNA3 | |
| SCHEMBL5380612 | 0.85 | FFAR1 (0.55) | FFAR1LTA4HEPHX2PPARG | |
| SCHEMBL4523232 | 0.84 | LTA4H (0.45) | DRD2DRD4DRD3FFAR1KCNA3 | |
| SCHEMBL4176154 | 0.84 | FFAR1 (0.64) | DRD2DRD4DRD3FFAR1KCNA3 | |
| SCHEMBL10738553 | 0.84 | FFAR1 (0.55) | DRD2DRD4DRD3FFAR1KCNA3 | |
| SCHEMBL4692389 | 0.84 | LTA4H (0.70) | FFAR1LTA4HEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |