Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939834 | 0.94 | LTA4H (0.56) | LTA4HEPHX2FFAR1ALDH1A1PLA2G4B | |
| SCHEMBL4517044 | 0.92 | LTA4H (0.72) | LTA4HEPHX2FFAR1ALDH1A1RECQL | |
| SCHEMBL4521863 | 0.89 | KCNA3 (0.59) | LTA4HEPHX2FFAR1KCNA3DRD2 | |
| SCHEMBL21483679 | 0.89 | LTA4H (0.57) | LTA4HEPHX2FFAR1ALDH1A1 | |
| SCHEMBL13932991 | 0.89 | LTA4H (0.72) | LTA4HEPHX2FFAR1ALDH1A1RECQL | |
| SCHEMBL4519292 | 0.87 | LTA4H (0.65) | LTA4HEPHX2FFAR1ALDH1A1RECQL | |
| SCHEMBL4659369 | 0.85 | LTA4H (0.73) | LTA4HEPHX2FFAR1ALDH1A1PLA2G4B | |
| SCHEMBL14463874 | 0.85 | LTA4H (0.77) | LTA4HEPHX2FFAR1ALDH1A1RECQL | |
| SCHEMBL13932452 | 0.85 | DRD2 (0.54) | LTA4HEPHX2FFAR1KCNA3DRD2 | |
| SCHEMBL10741496 | 0.83 | FFAR1 (0.55) | LTA4HEPHX2FFAR1KCNA3PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |