SCHEMBL139342

SCHEMBL139342

COc1ccc(C2(c3ccc(OC(=O)c4cccc(C(C)=O)c4)c(C)c3)CCCCC2)cc1C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PPARA Q07869 1/20 0.46
▸ ESR1 P03372 2/20 0.41
▸ ESR2 Q92731 2/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ ALDH1A1 P00352 6/20 0.40
▸ MAPT P10636 3/20 0.40
▸ TSHR P16473 2/20 0.39
▸ USP2 O75604 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ LMNA P02545 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19863502 0.98 PPARA (0.44) PPARAESR1ESR2MEN1KMT2A
SCHEMBL14007593 0.96 PPARA (0.44) PPARAESR1ESR2MEN1KMT2A
SCHEMBL19500464 0.95 PPARA (0.42) PPARAESR1ESR2MEN1KMT2A
SCHEMBL26431895 0.90 PPARA (0.45) PPARAESR1ESR2MEN1KMT2A
SCHEMBL12762427 0.90 PPARA (0.48) PPARAESR1ESR2MEN1KMT2A
SCHEMBL19863731 0.89 KMT2A (0.43) PPARAESR1ESR2MEN1KMT2A
SCHEMBL2743139 0.89 PPARA (0.52) PPARAESR1ESR2MEN1KMT2A
SCHEMBL19870993 0.87 PPARA (0.46) PPARAESR1ESR2MEN1KMT2A
SCHEMBL19870997 0.87 RARA (0.43) PPARAESR1ESR2MEN1KMT2A
SCHEMBL19863500 0.86 PPARA (0.41) PPARAESR1ESR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9482969-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2016-11-01 — — US disclosed
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 — — US disclosed
US-9201318-B2 Polymer for charge generation layer and charge transport layer formulation XEROX CORPORATION (US) 2015-12-01 — — US disclosed
US-9091949-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-07-28 — — US disclosed
US-9075327-B2 Imaging members and methods for making the same XEROX CORPORATION (US) 2015-07-07 — — US disclosed
US-20150177629-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION 2015-06-25 — — US disclosed
US-9046798-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-06-02 — — US disclosed
US-20150086914-A1 IMAGING MEMBERS AND METHODS FOR MAKING THE SAME XEROX CORPORATION (US) 2015-03-26 — — US disclosed
US-20150079510-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD THEREFOR, ELECTROPHOTOGRAPHIC DEVICE, AND PRODUCTION METHOD FOR COPOLYMER POLYARYLATE RESIN FUJI ELECTRIC CO., LTD. (JP) 2015-03-19 — — US disclosed
US-8835085-B2 Low strain anti-curl back coating for flexible imaging members XEROX CORPORATION (US) 2014-09-16 — — US disclosed
US-20140087297-A1 LOW STRAIN ANTI-CURL BACK COATING FOR FLEXIBLE IMAGING MEMBERS XEROX CORPORATION (US) 2014-03-27 — — US disclosed
US-20130143016-A1 ALTERNATE ANTICURL BACK COATING FORMULATION XEROX CORPORATION (US) 2013-06-06 — — US disclosed
US-8404414-B2 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2013-03-26 — — US disclosed
US-20120058422-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD (JP) 2012-03-08 — — US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 — — US disclosed
US-7901855-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2011-03-08 — — US disclosed
US-7875410-B2 capable opersistently exerting effect of mitigating contact stress with contact members and improved potential stability during repeated use; polycarbonates CANON KABUSHIKI KAISHA (JP) 2011-01-25 — — US disclosed
US-20100092208-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
US-20100092209-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
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