SCHEMBL19863502

SCHEMBL19863502

COc1ccc(C2(c3ccc(OC(=O)c4ccc(C(=O)Oc5ccc(C6(c7ccc(OC(=O)c8cccc(C(C)=O)c8)c(C)c7)CCCCC6)cc5C)cc4)c(C)c3)CCCCC2)cc1C

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PPARA Q07869 1/20 0.44
▸ ALDH1A1 P00352 6/20 0.41
▸ MAPT P10636 3/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ TSHR P16473 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ KMT2A Q03164 4/20 0.40
▸ MEN1 O00255 3/20 0.40
▸ ESR1 P03372 2/20 0.40
▸ ESR2 Q92731 2/20 0.40
▸ MAPK1 P28482 1/20 0.39
▸ USP2 O75604 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14007593 0.98 PPARA (0.44) PPARAALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL139342 0.98 PPARA (0.46) PPARAALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL19500464 0.95 PPARA (0.42) PPARAALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL12762427 0.92 PPARA (0.48) PPARAALDH1A1MAPTSMN1; SMN2KMT2A
SCHEMBL19863731 0.91 KMT2A (0.43) PPARAALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL26431895 0.91 PPARA (0.45) PPARAALDH1A1MAPTSMN1; SMN2KMT2A
SCHEMBL19870993 0.89 PPARA (0.46) PPARAALDH1A1MAPTSMN1; SMN2KMT2A
SCHEMBL2743139 0.89 PPARA (0.52) PPARAMAPTHPGDKMT2AMEN1
SCHEMBL19870997 0.89 RARA (0.43) PPARAALDH1A1MAPTSMN1; SMN2KMT2A
SCHEMBL19863500 0.88 PPARA (0.41) PPARAALDH1A1MAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180046098-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-02-15 — — US disclosed
US-20180046101-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-02-15 — — US disclosed
US-20180046100-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-02-15 — — US disclosed
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