Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.52 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31736881 | 1.00 | SLC2A1 (0.52) | SLC2A1GHSRGPR17GPR84ALDH1A1 | |
| SCHEMBL31736879 | 1.00 | SLC2A1 (0.52) | SLC2A1GHSRGPR17GPR84ALDH1A1 | |
| SCHEMBL1394536 | 1.00 | SLC2A1 (0.52) | SLC2A1GHSRGPR17GPR84ALDH1A1 | |
| SCHEMBL31736388 | 0.87 | SLC2A1 (0.50) | SLC2A1GHSRGPR84ALDH1A1HPGD | |
| SCHEMBL31736756 | 0.85 | SLC2A1 (0.57) | SLC2A1GHSRGPR84ALDH1A1HPGD | |
| SCHEMBL1393670 | 0.81 | SLC2A1 (0.39) | SLC2A1GPR17ALDH1A1HPGDKDM4E | |
| SCHEMBL31736947 | 0.76 | GHSR (0.62) | SLC2A1GHSRALDH1A1HPGDKDM4E | |
| SCHEMBL1349196 | 0.72 | GPR17 (0.38) | SLC2A1GPR17KDM4E | |
| SCHEMBL31736294 | 0.72 | SLC2A1 (0.57) | SLC2A1GHSRGPR84ALDH1A1HPGD | |
| SCHEMBL27959363 | 0.70 | GCGR (0.41) | HPGDMAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206131-B2 | Compounds having antiparasitic or anti-infectious activity | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2015-12-08 | — | — | US | disclosed |
| US-20140045888-A1 | COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2014-02-13 | — | — | US | disclosed |
| US-8598354-B2 | Compounds having antiparasitic or anti-infectious activity | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-12-03 | — | — | US | disclosed |
| WO-2012167237-A2 | COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY | MEDICINES FOR MALARIA VENTURE (CH) | 2012-12-06 | — | — | WO | disclosed |
| US-20120115904-A1 | COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY | 2012-05-10 | — | — | US | disclosed |
| US-20120010237-A1 | COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY | THE GOVERNMENT OF THE UNITED STATES OF AMERICA DBA THE DEPARTMENT OF VETERANS AFFAIRS | 2012-01-12 | — | — | US | disclosed |
| EP-2370411-A2 | COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY | Oregon Health and Science University (US) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010065905-A2 | COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010237-A1 | COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY | MASTL, RPS10, CBR3 | SLC2A1 3213/4885GHSR 3481/4885GPR17 3556/4885 |
| US-20140045888-A1 | COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY | H1-10, RAB10, HDAC10 | SLC2A1 4021/4885GHSR 2078/4885GPR17 3360/4885 |
| US-20120115904-A1 | COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY | H1-10, RAB10, HDAC10 | SLC2A1 3960/4885GHSR 1996/4885GPR17 3418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.