Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 4/20 | 0.40 |
| ▸ | CMA1 | P23946 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899974 | 0.86 | AHR (0.42) | GRIA1CACNG8AHRCMA1MAPK1 | |
| SCHEMBL13799364 | 0.83 | AHR (0.46) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL4976325 | 0.81 | GRIA1 (0.46) | GRIA1CACNG8AHRCMA1MAPK1 | |
| SCHEMBL5504321 | 0.79 | GRIA1 (0.39) | GRIA1CACNG8AHRCMA1MAPK1 | |
| SCHEMBL1436084 | 0.79 | GRIA1 (0.53) | GRIA1CACNG8AHRCMA1MAPK1 | |
| SCHEMBL5400154 | 0.75 | GRIA1 (0.44) | GRIA1CACNG8AHRCMA1MAPK1 | |
| SCHEMBL9051418 | 0.75 | GRIA1 (0.39) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL5498169 | 0.75 | PGR (0.41) | GRIA1CACNG8AHRCMA1MAPK1 | |
| SCHEMBL19751042 | 0.73 | AHR (0.50) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL12064436 | 0.73 | AHR (0.42) | GRIA1CACNG8AHRCMA1EIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062303-A1 | DEUTERIUM-ENRICHED ZIPRASIDONE | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062303-A1 | DEUTERIUM-ENRICHED ZIPRASIDONE | SLC39A3, SLC6A3, AVPR2 | GRIA1 1394/4885CACNG8 2961/4885AHR 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.