SCHEMBL13935567

SCHEMBL13935567

CCOC(=O)C1CC2OC2CC1C(=O)OCC1CCC2OC2C1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PPM1B O75688 2/20 0.49
▸ PTPN1 P18031 2/20 0.49
▸ PPP1CC P36873 2/20 0.49
▸ CYP3A4 P08684 2/20 0.35
▸ TP53 P04637 1/20 0.35
▸ MAPT P10636 2/20 0.35
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ CA12 O43570 2/20 0.32
▸ CA1 P00915 2/20 0.32
▸ CA2 P00918 2/20 0.32
▸ CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5425239 0.92 TP53 (0.40) PPM1BPTPN1PPP1CCCYP3A4TP53
SCHEMBL14163659 0.90 PPM1B (0.43) PPM1BPTPN1PPP1CCCYP3A4TP53
SCHEMBL28281069 0.87 PPM1B (0.35) PPM1BPTPN1PPP1CCCYP3A4TP53
SCHEMBL13935338 0.85 PPM1B (0.45) PPM1BPTPN1PPP1CCKMT2AALDH1A1
SCHEMBL11490731 0.84 TP53 (0.51) PPM1BPTPN1PPP1CCCYP3A4TP53
SCHEMBL4395179 0.83 PPM1B (0.55) PPM1BPTPN1PPP1CCCYP3A4MAPT
SCHEMBL4395174 0.83 PPM1B (0.55) PPM1BPTPN1PPP1CCCYP3A4MAPT
SCHEMBL7242807 0.82 TP53 (0.35) PPM1BPTPN1PPP1CCCYP3A4TP53
SCHEMBL22448093 0.82 TP53 (0.35) PPM1BPTPN1PPP1CCCYP3A4TP53
SCHEMBL12447862 0.82 PPM1B (0.33) PPM1BPTPN1PPP1CCCYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090041945-A1 ACTIVE RAY CURABLE COMPOSITION, POLYMERIZATION METHOD, ACTIVE RAY CURABLE INK, IMAGE FORMING METHOD, AND INK-JET RECORDING APPARATUS KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-02-12 — — US disclosed
US-20080180501-A1 Actinic Ray Curable Composition, Actinic Ray Curable Ink, Image Forming Method Utilizing the Same, Ink-Jet Recording Apparatus and Epoxy Compound KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 — — US disclosed
US-7390840-B2 Active ray curable composition, active ray curable ink, image forming method and inkjet recording apparatus utilizing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-06-24 — — US disclosed
US-20080107821-A1 Polymerizable Actinic Radiation Curable Composition, Polymerization Method, Actinic Radiation Curable Ink and Image Formation Method, and Ink Jet Recording Apparatus and Epoxy Compound KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-05-08 — — US disclosed
US-7360883-B2 Active ray curable ink, image forming method and ink-jet recording apparatus KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-04-22 — — US disclosed
EP-1840148-A1 POLYMERIZABLE ACTINIC RADIATION CURABLE COMPOSITION, POLYMERIZATION METHOD, ACTINIC RADIATION CURABLE INK AND IMAGE FORMATION METHOD, AND INK JET RECORDING APPARATUS AND EPOXY COMPOUND Konica Minolta Medical & Graphic, Inc. (JP) 2007-10-03 — — EP disclosed
EP-1837357-A1 ACTINIC RAY CURABLE COMPOSITION, ACTINIC RAY CURABLE INK, METHOD OF IMAGE FORMING THEREWITH, INKJET RECORDING APPARATUS AND EPOXY COMPOUND Konica Minolta Medical & Graphic, Inc. (JP) 2007-09-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080180501-A1 Actinic Ray Curable Composition, Actinic Ray Curable Ink, Image Forming Method Utilizing the Same, Ink-Jet Recording Apparatus and Epoxy Compound ROCK1, MACF1, ACTN1 PPM1B 836/4885PTPN1 1033/4885PPP1CC 209/4885
US-20080107821-A1 Polymerizable Actinic Radiation Curable Composition, Polymerization Method, Actinic Radiation Curable Ink and Image Formation Method, and Ink Jet Recording Apparatus and Epoxy Compound CBR3, CBR1, CNR1 PPM1B 1856/4885PTPN1 2645/4885PPP1CC 2156/4885
US-20090041945-A1 ACTIVE RAY CURABLE COMPOSITION, POLYMERIZATION METHOD, ACTIVE RAY CURABLE INK, IMAGE FORMING METHOD, AND INK-JET RECORDING APPARATUS RIF1, NAP1L4, NAP1L1 PPM1B 991/4885PTPN1 2404/4885PPP1CC 834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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