SCHEMBL1393763

SCHEMBL1393763

CCCCCCCCCCCCCCCCCCOC[C@H](COC(C(O)CO)P(=O)(O)O)OC(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50
LPAR3 Q9UBY5 8/20 0.49
LPAR1 Q92633 5/20 0.49
ENPP2 Q13822 3/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
LPAR2 Q9HBW0 3/20 0.48
LPAR6 P43657 1/20 0.48
LPAR4 Q99677 1/20 0.48
LPAR5 Q9H1C0 1/20 0.48
PRKCA P17252 1/20 0.48
PRKCE Q02156 1/20 0.48
PRKCQ Q04759 1/20 0.48
PRKCD Q05655 1/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
RECQL P46063 1/20 0.48
DAGLA Q9Y4D2 1/20 0.45
S1PR1 P21453 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4663594 1.00 MAPT (0.50) MAPTMAPK1LPAR3LPAR1ENPP2
SCHEMBL1429097 1.00 MAPT (0.50) MAPTMAPK1LPAR3LPAR1ENPP2
SCHEMBL667971 0.91 PRKCA (0.59) MAPTMAPK1LPAR3LPAR1ENPP2
SCHEMBL547251 0.90 ALDH1A1 (0.63) LPAR3LPAR1ENPP2SMN1; SMN2LPAR2
SCHEMBL42345 0.90 ALDH1A1 (0.63) LPAR3LPAR1ENPP2SMN1; SMN2LPAR2
SCHEMBL15052353 0.90 ALDH1A1 (0.63) LPAR3LPAR1ENPP2SMN1; SMN2LPAR2
SCHEMBL41701 0.90 ALDH1A1 (0.63) LPAR3LPAR1ENPP2SMN1; SMN2LPAR2
SCHEMBL3409080 0.90 ALDH1A1 (0.63) LPAR3LPAR1ENPP2SMN1; SMN2LPAR2
SCHEMBL16598280 0.90 ALDH1A1 (0.63) LPAR3LPAR1ENPP2SMN1; SMN2LPAR2
SCHEMBL4167244 0.90 ALDH1A1 (0.63) LPAR3LPAR1ENPP2SMN1; SMN2LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11173178-B2 Liposomes for drug delivery and methods for preparation thereof LIPLASOME PHARMA APS (DK) 2021-11-16 US disclosed
US-20200171080-A1 LIPOSOMES FOR DRUG DELIVERY AND METHODS FOR PREPARATION THEREOF LIPLASOME PHARMA APS (DK) 2020-06-04 US disclosed
EP-2299977-B1 LIPOSOMES FOR DRUG DELIVERY AND METHODS FOR PREPARATION THEREOF LIPLASOME PHARMA APS (DK) 2012-08-15 EP disclosed
US-20120009243-A1 LIPOSOMES FOR DRUG DELIVERY AND METHODS FOR PREPARATION THEREOF LIPLASOME PHARMA APS (DK) 2012-01-12 US disclosed
EP-2123258-A1 Liposomes for drug delivery Liplasome Pharma A/S (DK) 2009-11-25 EP disclosed