Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 13/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13938419 | 0.89 | DPP4 (0.59) | DPP4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL13923427 | 0.85 | ALDH1A1 (0.60) | MAOBDPP4L3MBTL1ALDH1A1LMNA | |
| SCHEMBL13938451 | 0.82 | MAOB (0.68) | MAOBDPP4L3MBTL1ALDH1A1LMNA | |
| SCHEMBL13939299 | 0.82 | MAOB (0.55) | MAOBDPP4L3MBTL1ALDH1A1LMNA | |
| SCHEMBL13923347 | 0.79 | ALDH1A1 (0.58) | MAOBDPP4ALDH1A1LMNAMAPT | |
| SCHEMBL13923351 | 0.79 | ALDH1A1 (0.59) | MAOBDPP4ALDH1A1LMNAMAPT | |
| SCHEMBL13923352 | 0.78 | ALDH1A1 (0.57) | MAOBDPP4ALDH1A1LMNAMAPT | |
| SCHEMBL13923426 | 0.78 | ALDH1A1 (0.60) | MAOBDPP4ALDH1A1LMNAMAPT | |
| SCHEMBL3897809 | 0.78 | ALDH1A1 (0.58) | MAOBDPP4ALDH1A1LMNAMAPT | |
| SCHEMBL13923358 | 0.78 | ALDH1A1 (0.56) | MAOBDPP4ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495004-B2 | Purine derivatives as liver X receptor agonists | GLAXO GROUP LIMITED (GB) | 2009-02-24 | — | — | US | disclosed |